Any deformity or disease of the nails in general is called:

The term that describes any deformity or disease of the nails is onychosis. This term is derived from the Greek word "onyx," which means nail, combined with the suffix that indicates a condition or state. Onychosis encompasses a wide range of nail disorders, including issues such as discoloration, deformities, and various infections.

Onychophosis refers specifically to a condition where there is a thickening of the outer layer of the nail, which is more specific than the general term for nail diseases. "Onyx" is simply another term for the nail itself, not related to any condition or disorder. Onychia, on the other hand, refers to an inflammation of the nail matrix, which is a specific condition rather than a broad term for nail disorders. Overall, onychosis effectively captures the concept of any abnormality or disease related to nails, making it the correct answer.